21.7.16

TCC and horseshoe kidney

Fig. 1. Horseshoe kidney with hydroureteronephrosis from the left side

74-YO patient with horseshoe kidney and hematuria. Hydroureteronephrosis from the left side. Soft tissue component in left ureter and in lt UVJ. Susp for Transitional cell carcinoma (TCC). 



Fig. 2. Horseshoe kidney with hydroureteronephrosis from the left side. Soft tissue component in left ureter. Condition after retroperitoneal lymph node dissection because of rt seminoma.
Fig. 3. Soft tissue component in left UVJ.

Stasis of urine and structural abnormalities such as horseshoe kidney are also associated with increased prevalence of TCC.

Synchronous bilateral TCC has been reported to occur in 1%–2% of cases of renal lesions and 2%–9% of cases of ureteric lesions.
Eleven percent to 13% of patients with upper tract TCC subsequently develop metachronous upper tract tumors.
Furthermore, up to 50% of patients initially presenting with upper tract TCC will develop metachronous tumors in the bladder, typically developing within 2 years of surgical treatment and seen more commonly with ureteric tumors than with renal tumors.
2% of patients with bladder TCC also have synchronous upper tract tumors at presentation, and 6% will develop metachronous upper tract disease.

CT urography is well established in the preoperative staging and assessment of upper tract TCC.